A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins
نویسندگان
چکیده
منابع مشابه
A Janus tale of two active high mobility group box 1 (HMGB1) redox states.
High mobility group box 1 (HMGB1), the prototypic damage-associated molecular pattern molecule, is released at sites of inflammation and/or tissue damage. There, it promotes cytokine production and chemokine production/cell migration. New work shows that the redox status of HMGB1 distinguishes its cytokine-inducing and chemokine activity. Reduced all-thiol-HMGB1 has sole chemokine activity, whe...
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High mobility group box 1 (HMGB 1): a new protein in the pathogenesis of ENT inflammatory and infectious diseases HMGB 1 una nuova proteina nella patogenesi della patologia infiammatoria ed infettiva ORL in addition to the well-known components of the immune response to inflammation, other inflammatory pathways have been recently invoked. Among these, an inflammatory molecule called high mobili...
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Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA; Department of Pathology, New York University School of Medicine, New York, New York 10016, USA; HUGO Gene Nomenclature Committee, Department of Biology, University College London, London, NW1 2HE, United Kingdom; Partners Center for Genetics and Genomics, Department of Genetics, Howard Hughes Medical Institute, H...
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ژورنال
عنوان ژورنال: Molecular Medicine
سال: 2014
ISSN: 1076-1551,1528-3658
DOI: 10.2119/molmed.2014.00022